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1

A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders, Camillo Porta

Journal:

BJU International

Year:

2011

Language:

english

File:

PDF, 567 KB

english, 2011

2

Alterations in VHL as potential biomarkers in renal-cell carcinoma

Gossage, Lucy, Eisen, Tim

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2010

Language:

english

File:

PDF, 388 KB

english, 2010

3

VHL, the story of a tumour suppressor gene

Gossage, Lucy, Eisen, Tim, Maher, Eamonn R.

Journal:

Nature Reviews Cancer

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

4

The CHRNA5–A3–B4 Gene Cluster and Smoking: From Discovery to Therapeutics

Lassi, Glenda, Taylor, Amy E., Timpson, Nicholas J., Kenny, Paul J., Mather, Robert J., Eisen, Tim, Munafò, Marcus R.

Journal:

Trends in Neurosciences

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

5

Results of a multicenter, randomized, double-blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma

Tim Eisen, Uwe Trefzer, Anne Hamilton, Peter Hersey, Michael Millward, Robert D. Knight, Jarl U. Jungnelius, John Glaspy

Journal:

Year:

2010

Language:

english

File:

PDF, 259 KB

english, 2010

6

Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects

Keiran S.M. Smalley, Tim G. Eisen

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 718 KB

english, 2002

7

Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells

Keiran S.M. Smalley, Tim G. Eisen

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 478 KB

english, 2003

8

Case-control study of familial lung cancer risks in UK women

Athena Matakidou, Tim Eisen, Helen Bridle, Mary O'Brien, Rosalind Mutch, Richard S. Houlston, Members of the GELCAPS Consortium

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 86 KB

english, 2005

9

Evaluation of xeroderma pigmentosum XPA, XPC, XPD, XPF, XPB, XPG and DDB2 genes in familial early-onset lung cancer predisposition

Athena Matakidou, Tim Eisen, Christina Fleischmann, Helen Bridle, Richard S. Houlston, Members of the GELCAPS Consortium

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 73 KB

english, 2006

10

Kinase inhibitors in the treatment of renal cell carcinoma

James M.G. Larkin, Tim Eisen

Journal:

Critical Reviews in Oncology/Hematology

Year:

2006

Language:

english

File:

PDF, 579 KB

english, 2006

11

Sentinel Lymph Node Biopsy (2001). Ed. Hiram Cody

Journal:

British Journal of Dermatology

Year:

2002

Language:

english

File:

PDF, 903 KB

english, 2002

12

Structural bioinformatics mutation analysis reveals genotype–phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis

Julia R. Forman, Catherine L. Worth, G. Richard J. Bickerton, Tim G. Eisen, Tom L. Blundell

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 333 KB

english, 2009

13

Quantitative trait locus and haplotype mapping in closely related inbred strains identifies a locus for open field behavior

Amy F. Eisener-Dorman, Laura Grabowski-Boase, Brian M. Steffy, Tim Wiltshire, Lisa M. Tarantino

Journal:

Mammalian Genome

Year:

2010

Language:

english

File:

PDF, 674 KB

english, 2010

14

Inherited variants inMYHare unlikely to contribute to the risk of lung carcinoma

Nada Al-Tassan, Tim Eisen, Julie Maynard, Helen Bridle, Bindiya Shah, Christina Fleischmann, JulianR. Sampson, JeremyP. Cheadle, RichardS. Houlston

Journal:

Year:

2004

Language:

english

File:

PDF, 276 KB

english, 2004

15

A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma

Simon Pacey, Martin Gore, David Chao, Udai Banerji, James Larkin, Sarah Sarker, Karen Owen, Yasmin Asad, Florence Raynaud, Mike Walton, Ian Judson, Paul Workman, Tim Eisen

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

16

Perspectives in drug development for metastatic renal cell cancer

Bristi Basu, Tim Eisen

Journal:

Targeted Oncology

Year:

2010

Language:

english

File:

PDF, 580 KB

english, 2010

17

The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells

La’Verne P. Rennalls, Thomas Seidl, James M. G. Larkin, Claudia Wellbrock, Martin E. Gore, Tim Eisen, Ludovica Bruno

Journal:

Year:

2010

Language:

english

File:

PDF, 559 KB

english, 2010

18

Surgical excision of isolated renal-bed recurrence after radical nephrectomy for renal cell carcinoma

Sarbjinder S. Sandhu, Andrew Symes, Roger A’hern, S.A. Aslam Sohaib, Tim Eisen, Martin Gore, Timothy J. Christmas

Journal:

BJU International

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

19

Prognostic factors in renal cell cancer

Won-Ho Park, Tim Eisen

Journal:

BJU International

Year:

2007

Language:

english

File:

PDF, 75 KB

english, 2007

20

THE NATIONAL INSTITUTE OF HEALTH AND CLINICAL EXCELLENCE REJECTS NEW TREATMENTS FOR RENAL CELL CANCER: CINDERELLA'S INVITATION IS CANCELLED

Journal:

BJU International

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

21

Systemic therapy for metastatic malignant melanoma – from deeply disappointing to bright future?

Paul Lorigan, Tim Eisen, Axel Hauschild

Journal:

Experimental Dermatology

Year:

2008

Language:

english

File:

PDF, 131 KB

english, 2008

22

ICUD-EAU International Consultation on Kidney Cancer 2010: Treatment of Metastatic Disease

Jean-Jacques Patard, Geraldine Pignot, Bernard Escudier, Tim Eisen, Axel Bex, Cora Sternberg, Brian Rini, Jan Roigas, Toni Choueiri, Ronald Bukowski, Robert Motzer, Ziya Kirkali, Peter Mulders, Joaqui

Journal:

European Urology

Year:

2011

Language:

english

File:

PDF, 275 KB

english, 2011

23

Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)

Tim Eisen, Athena Matakidou, Richard Houlston, the GELCAPS Consortium

Journal:

Year:

2008

Language:

english

File:

PDF, 310 KB

english, 2008

24

Adjuvant Therapy of Renal Cell Carcinoma

Timothy A. Yap, Tim G. Eisen

Journal:

Clinical Genitourinary Cancer

Year:

2006

Language:

english

File:

PDF, 175 KB

english, 2006

25

Treating the individual: The need for a patient-focused approach to the management of renal cell carcinoma

Camillo Porta, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders

Journal:

Cancer Treatment Reviews

Year:

2010

Language:

english

File:

PDF, 366 KB

english, 2010

26

Renewed hope for patients with advanced renal cell cancer: Cinderella comes of age

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 84 KB

english, 2005

27

Long-term safety of sorafenib in advanced renal cell carcinoma: Follow-up of patients from phase III TARGET

Thomas E. Hutson, Joaquim Bellmunt, Camillo Porta, Cezary Szczylik, Michael Staehler, Andrea Nadel, Sibyl Anderson, Ronald Bukowski, Tim Eisen, Bernard Escudier

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

28

Reducing sample sizes in two-stage phase II cancer trials by using continuous tumour shrinkage end-points

James M.S. Wason, Adrian P. Mander, Tim G. Eisen

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 397 KB

english, 2011

29

The involvement of p38 mitogen-activated protein kinase in the α-melanocyte stimulating hormone (α-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells

Keiran Smalley, Tim Eisen

Journal:

Year:

2000

Language:

english

File:

PDF, 270 KB

english, 2000

30

The biological treatment of renal-cell carcinoma and melanoma

Paul D Nathan, Tim G Eisen

Journal:

The Lancet Oncology

Year:

2002

Language:

english

File:

PDF, 177 KB

english, 2002

31

Cancer biology for the clinic and the lab

Journal:

Trends in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 29 KB

english, 2002

32

Adjuvant Therapy in Renal Cell Carcinoma: Where Are We?

Journal:

European Urology Supplements

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

33

Current Status of Targeted Therapy in Metastatic Renal Cell Carcinoma

Pieter H.M. De Mulder, Jean-Jaques Patard, Cezary Szczylik, Thomas Otto, Tim Eisen

Journal:

European Urology Supplements

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

34

Small-cell lung cancer: Report of a Meeting of POhysicians and Scientists at the Royal Marsden Hospital, Sutto, UK

Tim Eisen, Tamas Hickish, I.E. Smith, John Sloane, Suzanne Eccles

Journal:

Year:

1995

Language:

english

File:

PDF, 658 KB

english, 1995

35

Rehabilitation in Croatia

Journal:

Year:

1995

Language:

english

File:

PDF, 193 KB

english, 1995

36

O-251 Weight loss and anaemia are poor prognostic factors for patients with lung cancer receiving chemotherapy — will modification of these prognostic factors become a new standard of care?

Ross, Paul J., Waters, Justin S., Ashley, Sue, Priest, Kathy, Norton, Alison, Eisen, Tim, Smith, Ian E., O'Brien, Mary E.R.

Journal:

Year:

2003

Language:

english

File:

PDF, 369 KB

english, 2003

37

P-98 Establishment of a DNA resource through the GELCAPS consortium to study low penetrance susceptibility alleles for lung cancer

Matakidou, Athena, Eisen, Tim, O'Brien, Mary E.R., Houlston, Richard S.

Journal:

Year:

2003

Language:

english

File:

PDF, 166 KB

english, 2003

38

P-536 Final results of a phase II study of alternating navelbine (NVB) oral and intravenous in combination with carboplatin(C) in advanced non-small cell lung cancer (NSCLC)

O'Brien, Mary E.R., Szeczesna, Aleksandra, Karnicka, Hanna, Zatloukal, Petr, Eisen, Tim, Hartmann, Wielfried, Kasan, Peter, Longerey, Blandine, Lefresne, Florence

Journal:

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

39

The association of chemotherapy induced neutropenia on treatment outcomes in small cell lung cancer

Banerji, Udai, Ashley, Sue, Coward, Jim, Hughes, Sarah, Zee, Ying, Benepal, Taqdir, Norton, Alison, Eisen, Tim, O’Brien, Mary

Journal:

Year:

2006

Language:

english

File:

PDF, 312 KB

english, 2006

40

Lack of evidence that p53 Arg72Pro influences lung cancer prognosis: An analysis of survival in 619 female patients

Matakidou, Athena, el Galta, Rachid, Webb, Emily L., Rudd, Matthew F., Bridle, Helen, Eisen, Tim, Houlston, Richard S.

Journal:

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

41

Ensuring the right PET scan for the right patient

Spiro, Stephen G., Buscombe, John, Cook, Gary, Eisen, Tim, Gleeson, Fergus, O’Brien, Mary, Peake, Michael D., Rowell, Nicholas P., Seymour, Richard

Journal:

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

42

Phase II study of weekly plitidepsin as second-line therapy for small cell lung cancer

Eisen, Tim, Thatcher, Nick, Leyvraz, Serge, Miller, Wilson H., Couture, Felix, Lorigan, Paul, Lüthi, François, Small, David, Tanovic, Adnan, O’Brien, Mary

Journal:

Year:

2009

Language:

english

File:

PDF, 143 KB

english, 2009

43

Plasminogen activator inhibitor variants PAI-1 A15T and PAI-2 S413C influence lung cancer prognosis

Di Bernardo, Maria Chiara, Matakidou, Athena, Eisen, Tim, Houlston, Richard S.

Journal:

Year:

2009

Language:

english

File:

PDF, 390 KB

english, 2009

44

Regorafenib for patients with previously untreated metastatic or unresectable renal-cell carcinoma: a single-group phase 2 trial

Tim Eisen, Heikki Joensuu, Paul D Nathan, Peter G Harper, Marek Z Wojtukiewicz, Steve Nicholson, Amit Bahl, Piotr Tomczak, Seppo Pyrhonen, Kate Fife, Petri Bono, Jane Boxall, Andrea Wagner, Michael Je

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 231 KB

english, 2012

45

Immunotherapeutic strategies in kidney cancer—when TKIs are not enough

Biswas, Swethajit, Eisen, Tim

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

46

Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma

Escudier, Bernard, Eisen, Tim, Stadler, Walter M., Szczylik, Cezary, Oudard, Stéphane, Siebels, Michael, Negrier, Sylvie, Chevreau, Christine, Solska, Ewa, Desai, Apurva A., Rolland, Frédéric, Demkow,

Journal:

Boston Medical and Surgical Journal

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

47

Regorafenib (BAY 73–4506): Stromal and Oncogenic Multikinase Inhibitor with Potential Activity in Renal Cell Carcinoma

Kamarul Zaki, Shahzeena Aslam, Tim Eisen

Journal:

Current Oncology Reports

Year:

2013

Language:

english

File:

PDF, 206 KB

english, 2013

48

Adjuvant Therapy in Renal Cell Carcinoma—Past, Present, and Future

Janowitz, Tobias, Welsh, Sarah J., Zaki, Kamarul, Mulders, Peter, Eisen, Tim

Journal:

Seminars in Oncology

Year:

2013

Language:

english

File:

PDF, 640 KB

english, 2013

49

Naptumomab Estafenatox: Targeted Immunotherapy with a Novel Immunotoxin

Eisen, Tim, Hedlund, Gunnar, Forsberg, Göran, Hawkins, Robert

Journal:

Current Oncology Reports

Year:

2014

Language:

english

File:

PDF, 252 KB

english, 2014

50

Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma

Harmon, Charles S., DePrimo, Samuel E., Figlin, Robert A., Hudes, Gary R., Hutson, Thomas E., Michaelson, M. Dror, Négrier, Sylvie, Kim, Sindy T., Huang, Xin, Williams, J. Andrew, Eisen, Tim, Motzer,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

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